99ae46aca64e768875e6cbb2a232a0648bea5344 max Fri May 15 10:13:21 2026 -0700 varFreqs: prefix non-downloadable /gbdb subdirs with "_" so hgdownload rsync skips them; update bigDataUrl paths and Data Access wording on description pages for topmed, allofus, sfariSparkExomes/sfariSparkWgs, and mxbFreq. Combined varFreqsAll.bb moved into _all/. refs #36642 Co-Authored-By: Claude Opus 4.7 (1M context) diff --git src/hg/makeDb/trackDb/human/mxbFreq.html src/hg/makeDb/trackDb/human/mxbFreq.html index c85f4d06748..62cc6748103 100644 --- src/hg/makeDb/trackDb/human/mxbFreq.html +++ src/hg/makeDb/trackDb/human/mxbFreq.html @@ -8,31 +8,35 @@ variants. Only autosomal, biallelic SNPs passing quality control are included. Samples were selected from 898 recruitment sites, with prioritization of indigenous language speakers.

This track shows allele frequencies computed from the phased genotypes. The full phased genotype data with haplotype clustering display is available in the Mexico Biobank track under Phased Variants. Frequencies can also be plotted onto a map on the MexVar platform. The hg38 data was lifted from hg19 by UCSC (see below).

Data Access

-We are not allowed to redistribute the VCF file. +Due to license restrictions, the data for this track cannot be downloaded from the UCSC +Genome Browser. The Table Browser, Data Integrator, and download server are not available +for this track. +

+

Allele frequencies by geographical state and ancestry are available via the MexVar platform. Raw genotype data are available under controlled access at the EGA (Study: EGAS00001005797; Dataset: EGAD00010002361). For the VCFs, email andres.moreno@cinvestav.mx to obtain the data.

Methods

Data processing included GenomeStudio → PLINK conversion, strand alignment, removal of duplicates, update of map positions using dbSNP Build 151 and low-quality variants/individuals, and relatedness filtering. At UCSC, the phased VCF was lifted from hg19 to hg38 with CrossMap, then allele counts (AC, AF, AN) were computed using bcftools fill-tags and genotypes were stripped to produce a sites-only frequency VCF.