99ae46aca64e768875e6cbb2a232a0648bea5344 max Fri May 15 10:13:21 2026 -0700 varFreqs: prefix non-downloadable /gbdb subdirs with "_" so hgdownload rsync skips them; update bigDataUrl paths and Data Access wording on description pages for topmed, allofus, sfariSparkExomes/sfariSparkWgs, and mxbFreq. Combined varFreqsAll.bb moved into _all/. refs #36642 Co-Authored-By: Claude Opus 4.7 (1M context) <noreply@anthropic.com> diff --git src/hg/makeDb/trackDb/human/mxbFreq.html src/hg/makeDb/trackDb/human/mxbFreq.html index c85f4d06748..62cc6748103 100644 --- src/hg/makeDb/trackDb/human/mxbFreq.html +++ src/hg/makeDb/trackDb/human/mxbFreq.html @@ -8,31 +8,35 @@ variants. Only autosomal, biallelic SNPs passing quality control are included. Samples were selected from 898 recruitment sites, with prioritization of indigenous language speakers. </p> <p> This track shows allele frequencies computed from the phased genotypes. The full phased genotype data with haplotype clustering display is available in the <a href="hgTrackUi?g=mexbb">Mexico Biobank track</a> under Phased Variants. Frequencies can also be plotted onto a map on the <a href="https://morenolab.shinyapps.io/mexvar/" target="_blank">MexVar platform</a>. The hg38 data was lifted from hg19 by UCSC (see below). </p> <h2>Data Access</h2> <p> -We are not allowed to redistribute the VCF file. +Due to license restrictions, the data for this track cannot be downloaded from the UCSC +Genome Browser. The Table Browser, Data Integrator, and download server are not available +for this track. +</p> +<p> Allele frequencies by geographical state and ancestry are available via the <a href="https://morenolab.shinyapps.io/mexvar/" target="_blank">MexVar platform</a>. Raw genotype data are available under controlled access at the EGA (Study: EGAS00001005797; Dataset: EGAD00010002361). For the VCFs, email andres.moreno@cinvestav.mx to obtain the data. </p> <h2>Methods</h2> <p> Data processing included GenomeStudio → PLINK conversion, strand alignment, removal of duplicates, update of map positions using dbSNP Build 151 and low-quality variants/individuals, and relatedness filtering. At UCSC, the phased VCF was lifted from hg19 to hg38 with CrossMap, then allele counts (AC, AF, AN) were computed using bcftools fill-tags and genotypes were stripped to produce a sites-only frequency VCF.