4f8f8773bec66a9e993e9897e0b032c6e97dead8 max Fri May 15 10:12:29 2026 -0700 mei: add HMEID, SweGen, and euL1db subtracks Three new MEI catalogues under the existing mei superTrack: meiHmeid (hg38) 36,699 MELT MEIs from HMEID v1.1 (NyuWa+1KGP, 5,675 individuals, Niu et al. 2022, PMID 35212372). Site-level VCF; per-cohort and per-1KGP super- population AC/AN/AF; SVTYPE Alu/L1/SVA/HERVK. meiSwegen (hg38 lifted) 18,090 MELT MEIs from the SweGen 1,000-sample Swedish cohort (Ameur 2017, PMID 28832569; Gardner 2017, PMID 28855259). Built on hg19, liftOver to hg38 (10 unmapped). tableBrowser off per SweGen distribution terms. meiEul1db (hg19+hg38) 8,988 curated L1-HS insertion polymorphisms (MRIPs) from euL1db v1.00 (Mir 2015, PMID 25352549), aggregating 142,495 sample-level SRIPs across 32 published studies. Coloured by lineage (germline/somatic/mixed). Built on hg19, liftOver to hg38 (3 unmapped). Helman2014 used numeric chrom names (23=X, 24=Y) which are renamed during the build. meiEul1dbRef (hg19+hg38) 1,540 reference-genome L1-HS copies catalogued by euL1db (companion to meiEul1db). Single shared mei.ra (in human/) uses $D substitution so each stanza serves both assemblies where applicable. refs #37524 diff --git src/hg/makeDb/scripts/mei/meiEul1dbRef.as src/hg/makeDb/scripts/mei/meiEul1dbRef.as new file mode 100644 index 00000000000..7569ab67e94 --- /dev/null +++ src/hg/makeDb/scripts/mei/meiEul1dbRef.as @@ -0,0 +1,19 @@ +table meiEul1dbRef +"euL1db: L1-HS copies present in the human reference genome" +( +string chrom; "Reference chromosome" +uint chromStart; "0-based start of reference L1HS element" +uint chromEnd; "Half-open end of reference L1HS element" +string name; "Subgroup label (L1HS-Ta, L1HS-PreTa, L1HS-Hybrid)" +uint score; "Score (unused, 0)" +char[1] strand; "Strand" +uint thickStart; "Start of thick drawing region" +uint thickEnd; "End of thick drawing region" +uint itemRgb; "RGB color, by L1HS subgroup" +string family; "Family|Always L1HS" +string subGroup; "Sub-group|L1HS-Ta, L1HS-PreTa, L1HS-Hybrid" +string integrity; "Integrity|full-length or 5prime-truncated" +uint refStart; "Position on L1HS consensus|5' start in L1HS consensus sequence" +uint refStop; "Position on L1HS consensus|3' stop in L1HS consensus sequence" +uint elementLen; "Element length (bp)" +)