9bfd58221b1539193cb7f0a317b4e959c1c7e49a
max
Thu May 21 01:00:45 2026 -0700
varFreqs: AI generated text sounds bad, hard to read, so remove typical AI language. "humanizer" pass on all 31 varFreqs description pages — cut em dashes, copula avoidance ("serves as", "stands as"), "-ing" puffery, and boilerplate filler ("We provide documentation that indicates how..."). Title-case headings and meaningful <b> emphasis preserved. No facts/URLs/counts/versions changed. tpmi.html added as a new file (was previously uncommitted). refs #36642
Co-Authored-By: Claude Sonnet 4.6 <noreply@anthropic.com>
diff --git src/hg/makeDb/trackDb/human/sfariSparkExomes.html src/hg/makeDb/trackDb/human/sfariSparkExomes.html
index 27e11ff2610..f3428e3fa2a 100644
--- src/hg/makeDb/trackDb/human/sfariSparkExomes.html
+++ src/hg/makeDb/trackDb/human/sfariSparkExomes.html
@@ -93,28 +93,28 @@
(CHIP). SFARI performed SNV/indel calling via DeepVariant and
GATK to generate gVCFs, pairwise relatedness inferred using
PLINK v1.9 IBD estimates from common SNPs (AF ≥ 0.01, dbSNP
v151) with ≥15% relatedness flagged, and comprehensive
individual- and family-level quality control executed using the
internal GenomeCheckMate pipeline to exclude samples based on
contamination (≥5%), insufficient coverage (<20x in <80% of
targets), sex discordance, pedigree/IBD inconsistencies,
unregistered relationships, unexpected duplicates, or excess
relatedness, after which QC-passing individuals (selecting the
most recent passing sample per person) were retained for
variant calling and joint genotyping.
</li>
</ul>
<p>
-We provide documentation that indicates how all source files of the varFreqs track were converted in the <a href="https://github.com/ucscGenomeBrowser/kent/blob/master/src/hg/makeDb/doc/hg38/varFreqs.txt" target="_blank">makeDoc file</a> of the track.
+The <a href="https://github.com/ucscGenomeBrowser/kent/blob/master/src/hg/makeDb/doc/hg38/varFreqs.txt" target="_blank">makeDoc file</a> documents how all source files of the varFreqs track were converted.
For some tracks, python scripts were necessary and are also available from <a href="https://github.com/ucscGenomeBrowser/kent/blob/master/src/hg/makeDb/scripts/varFreqs" target="_blank">GitHub</a>.
</p>
<h2>References</h2>
<p>
SPARK Consortium. Electronic address: <A HREF="mailto:pfeliciano@simonsfoundation.org">pfeliciano@simonsfoundation.org</A><!-- above address is pfeliciano at simonsfoundation.org -->, SPARK Consortium.
<a href="https://linkinghub.elsevier.com/retrieve/pii/S0896-6273(18)30018-7" target="_blank">
SPARK: A US Cohort of 50,000 Families to Accelerate Autism Research</a>.
<em>Neuron</em>. 2018 Feb 7;97(3):488-493.
PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/29420931" target="_blank">29420931</a>; PMC: <a
href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444276/" target="_blank">PMC7444276</a>
</p>