753e4fdfc8b960c8a8775e2282b0f87c73a95449
lrnassar
  Tue Jun 2 07:49:03 2026 -0700
varFreqsDisease.html: list six disease cohorts separately to match the
"six cohorts" count in the opening sentence and the six per-source AC/AF
columns in the bigBed schema. SPARK WES and SFARI WGS are two distinct
sample sets, not one combined cohort. Per QA feedback. refs #36642

diff --git src/hg/makeDb/trackDb/human/varFreqsDisease.html src/hg/makeDb/trackDb/human/varFreqsDisease.html
index 613013eac96..010d65019b7 100644
--- src/hg/makeDb/trackDb/human/varFreqsDisease.html
+++ src/hg/makeDb/trackDb/human/varFreqsDisease.html
@@ -1,24 +1,24 @@
 <h2>Description</h2>
 <p>
 This track merges variants from six disease-focused or clinically-recruited cohorts into a
 single bigBed file with predicted protein consequences and cross-database filtering. It
-contains 932 million variants from SFARI SPARK (WES + WGS, autism families), TOPMed
-(NHLBI heart, lung and blood disease cohorts), SCHEMA (schizophrenia case/control),
-GREGoR (rare-disease families), and GA4K (PacBio long-read pediatric rare disease). Where
-the source dataset provides per-phenotype counts, those are exposed as separate AC/AF
-columns and as filter widgets.
+contains 932 million variants from SPARK WES (140k autism families), SFARI WGS (12.5k
+autism families), TOPMed (NHLBI heart, lung and blood disease cohorts), SCHEMA
+(schizophrenia case/control), GREGoR (rare-disease families), and GA4K (PacBio long-read
+pediatric rare disease). Where the source dataset provides per-phenotype counts, those are
+exposed as separate AC/AF columns and as filter widgets.
 </p>
 
 <p>
 For a summary of all available variant frequency databases, including the population-scale
 control track and the genotyping-array track, see the
 <a href="hgTrackUi?g=varFreqs">SNV Frequencies</a> supertrack page.
 </p>
 
 <p>
 Each variant is annotated with its predicted consequence on protein-coding genes
 (using <a href="https://samtools.github.io/bcftools/howtos/csq-calling.html"
 target="_blank">bcftools csq</a> with
 <a href="https://www.ensembl.org/info/data/ftp/index.html" target="_blank">Ensembl</a>
 gene models), and colored by severity. Allele counts and frequencies are shown for each
 source database and, where available, broken down by phenotype.