a98dfd4707e69c1617982e26ddf3310a8b7a3277 mspeir Fri Sep 4 10:11:06 2026 -0700 relatedTracks.ra: relate OMIM to GenCC, Orphanet and G2P The gene-disease cluster added in the previous commit was built around GenCC as a hub, with every spoke sharing the reason "one of the sources GenCC aggregates". OMIM is not a GenCC submitter, so it never matched that phrasing and ended up connected only to GeneReviews, despite being the reference the other resources cite. The related-track cap was not the constraint; GenCC was at four of five and OMIM at one of five. Adds three reciprocal pairs on hg38 and hg19: OMIM with GenCC, with Orphanet and with G2P. GenCC now sits at its cap of five and OMIM at four. PanelApp is left out on purpose. Its panels do cite OMIM, but including it would put five gene-disease resources on OMIM's page mostly describing one another, and PanelApp is the most specialized of them. refs #38016 Co-Authored-By: Claude Opus 5 (1M context) <noreply@anthropic.com> diff --git src/hg/makeDb/trackDb/relatedTracks.ra src/hg/makeDb/trackDb/relatedTracks.ra index 1252d33ac80..148bc8a254b 100644 --- src/hg/makeDb/trackDb/relatedTracks.ra +++ src/hg/makeDb/trackDb/relatedTracks.ra @@ -270,41 +270,53 @@ hg19 lovdComp clinvar Variant interpretations submitted by clinical laboratories worldwide hg19 clinvar decipherContainer Patient variants and CNVs from the DECIPHER developmental disorder database hg19 decipherContainer clinvar Variant interpretations submitted by clinical laboratories, with review status # Gene-disease curation cross-links: hg38 genCC g2p Gene-disease pairs curated by the Gene2Phenotype project, one of the sources GenCC aggregates hg38 g2p genCC Gene-disease assertions from several curation groups, harmonized into one set hg38 genCC panelApp Diagnostic gene panels from Genomics England and Australia, one of the sources GenCC aggregates hg38 panelApp genCC Gene-disease assertions from several curation groups, harmonized into one set hg38 genCC orphadata Rare disease gene annotations from Orphanet, one of the sources GenCC aggregates hg38 orphadata genCC Gene-disease assertions from several curation groups, harmonized into one set hg38 genCC clinGenComp Expert-panel gene-disease validity and dosage sensitivity curation, one of the sources GenCC aggregates hg38 clinGenComp genCC Gene-disease assertions from several curation groups, harmonized into one set hg38 geneReviews omimContainer Gene and phenotype records from OMIM, the standard reference for Mendelian disease genes hg38 omimContainer geneReviews Expert-authored clinical summaries for genetic conditions, with diagnosis and management guidance +hg38 genCC omimContainer Gene and phenotype records from OMIM, the reference these curation efforts cite +hg38 omimContainer genCC Gene-disease assertions from several curation groups, harmonized into one set +hg38 orphadata omimContainer Gene and phenotype records from OMIM, cross-referenced throughout Orphanet +hg38 omimContainer orphadata Rare disease gene annotations from Orphanet +hg38 g2p omimContainer Gene and phenotype records from OMIM, the reference these curation efforts cite +hg38 omimContainer g2p Gene-disease pairs curated by the Gene2Phenotype project hg19 genCC g2p Gene-disease pairs curated by the Gene2Phenotype project, one of the sources GenCC aggregates hg19 g2p genCC Gene-disease assertions from several curation groups, harmonized into one set hg19 genCC panelApp Diagnostic gene panels from Genomics England and Australia, one of the sources GenCC aggregates hg19 panelApp genCC Gene-disease assertions from several curation groups, harmonized into one set hg19 genCC orphadata Rare disease gene annotations from Orphanet, one of the sources GenCC aggregates hg19 orphadata genCC Gene-disease assertions from several curation groups, harmonized into one set hg19 genCC clinGenComp Expert-panel gene-disease validity and dosage sensitivity curation, one of the sources GenCC aggregates hg19 clinGenComp genCC Gene-disease assertions from several curation groups, harmonized into one set hg19 geneReviews omimContainer Gene and phenotype records from OMIM, the standard reference for Mendelian disease genes hg19 omimContainer geneReviews Expert-authored clinical summaries for genetic conditions, with diagnosis and management guidance +hg19 genCC omimContainer Gene and phenotype records from OMIM, the reference these curation efforts cite +hg19 omimContainer genCC Gene-disease assertions from several curation groups, harmonized into one set +hg19 orphadata omimContainer Gene and phenotype records from OMIM, cross-referenced throughout Orphanet +hg19 omimContainer orphadata Rare disease gene annotations from Orphanet +hg19 g2p omimContainer Gene and phenotype records from OMIM, the reference these curation efforts cite +hg19 omimContainer g2p Gene-disease pairs curated by the Gene2Phenotype project # Cancer somatic variant cross-links: hg38 cancerMutations gdcCancer The same TCGA somatic mutations, summarized across all 33 Pan-Cancer projects hg38 gdcCancer cancerMutations TCGA somatic mutations shown separately for each cancer study hg38 cosmicMuts civic Clinically interpreted cancer variants, with evidence for diagnosis, prognosis and drug response hg38 civic cosmicMuts A broad catalog of somatic mutations reported in cancer, without clinical interpretation hg38 gdcCancer cancerExpr Gene expression measured in the same 33 TCGA cancer projects hg38 cancerExpr gdcCancer Somatic mutations called in the same 33 TCGA cancer projects hg38 >dbVar_somatic cosmicMuts A much larger catalog of somatic point mutations in cancer hg19 cosmicMuts civic Clinically interpreted cancer variants, with evidence for diagnosis, prognosis and drug response hg19 civic cosmicMuts A broad catalog of somatic mutations reported in cancer, without clinical interpretation hg19 >dbVar_somatic cosmicMuts A much larger catalog of somatic point mutations in cancer # Structural variation cross-links: