17b7d3c37be41135afaf8e91e365e3847af96ca5 lrnassar Mon Jun 22 10:56:56 2026 -0700 Add TAD (topologically associating domains) track set on hg19, hg38, mm10, mm39. refs #21599 New "tads" superTrack collecting published TAD calls, alpha-gated via include tad.ra alpha in each assembly's trackDb.ra. hg38 (all five sources): Dixon 2012 domains, Schmitt 2016 boundaries, McArthur & Capra 2021 boundary stability, ENCODE contact domains (faceted composite over 117 biosamples), and 3D Genome Browser 2.0 domains (faceted composite over 464 datasets). hg19: the three sources with hg19-compatible data (Dixon, Schmitt, McArthur). mm10/mm39 (domains only; the boundary sources have no mouse data): Dixon, ENCODE (faceted, 16 biosamples), and 3D Genome Browser (faceted, 30 datasets); mm39 lifted from mm10, lift noted in the long labels. Faceted composites are organ-colored from a TAD-owned organ_colors.json symlinked into /gbdb/<asm>/bbi/tad/. Build scripts and autoSql are version-controlled under makeDb/scripts/tad/ and symlinked into the per-source build dirs. Provenance and fetch for every dataset are documented in the makedocs (doc/hg38/tad.txt, doc/mm10/tad.txt, doc/mm39/tad.txt, and the hg19 TAD section in doc/hg19.txt). diff --git src/hg/makeDb/scripts/tad/tadDomainEncode.as src/hg/makeDb/scripts/tad/tadDomainEncode.as new file mode 100644 index 00000000000..75b3959b575 --- /dev/null +++ src/hg/makeDb/scripts/tad/tadDomainEncode.as @@ -0,0 +1,13 @@ +table tadDomainEncode +"ENCODE contact-domain (TAD) interval with Arrowhead corner-detection scores" + ( + string chrom; "Chromosome" + uint chromStart; "Domain start" + uint chromEnd; "Domain end" + string name; "Biosample" + float cornerScore; "Arrowhead corner score: likelihood this is a contact-domain corner (higher = stronger)" + float uVarScore; "Variance of the upper triangle of the domain contact submatrix" + float lVarScore; "Variance of the lower triangle of the domain contact submatrix" + float upSign; "Upper-triangle sign score: -1 x sum of signs of upper-triangle entries" + float loSign; "Lower-triangle sign score: sum of signs of lower-triangle entries" + )