2c7413be1d0412785eb7238454dacefc57de05bc angie Tue Mar 10 15:53:08 2026 -0700 Mask reversions caused by dropout in BA.3.2 diff --git src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml index 5737b7d37ce..ca7d7436ffc 100644 --- src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml +++ src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml @@ -153,32 +153,39 @@ KP.1: # Inherits from JN.1 representative: England/CLIMB-CM7YEN1U/2024 reversions: [ T17334G # Reversion of JN.1.11.1 mutation, email from FedeGueli ] KP.3.1.1: # Inherits from JN.1 representative: England/CLIMB-CM7YJCHG/2024 reversions: [ C22926T, # https://github.com/sars-cov-2-variants/lineage-proposals/issues/1914 C22928T, # '' # Others I noticed while looking at the above: G7842A, T23948G, C3565T, T17334G, G19722A, G23055A, T28271A, T23063A, G22910A ] +BA.3.2: + # No inheritance + representative: SouthAfrica/NICD-N58822/2024 + representativeBacktrack: 2 + reversions: [ C27382G, A27395T, T27807C # dropout in Netherlands sequences + ] + RE.1.1: - # No inheritance -- BA.3.2 descendant with lots of dropout in Australia/WA sequences + # Inherits from BA.3.2; lots of dropout in Australia/WA sequences # https://github.com/sars-cov-2-variants/lineage-proposals/issues/3093#issuecomment-3508425340 representative: Australia/WA17392/2025 reversions: [ A336G, C13375T, C22629A, T28996A ] sites: [ 28254 ] BA.4: # BA.4 is placed on the BA.2 branch so it inherits all the BA.2 sites. representative: SouthAfrica/NICD-N41664/2022 ranges: [ [ 686, 694 ], [ 21765, 21770 ] ] BA.5: # BA.5 is placed on the BA.2 branch so it inherits all the BA.2 sites. representative: England/PHEP-YYFJPAM/2022 ranges: [ [ 21765, 21770 ] ] # Some of these should be reverted in recombinants, but we're pretty much past the point of