366028b554770e59a35f881811dd006c047ce9c6 angie Thu Dec 4 15:32:59 2025 -0800 Added RE.1.1 reversions and site requested by @ryhisner diff --git src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml index 25c285d0d5c..5737b7d37ce 100644 --- src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml +++ src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml @@ -153,30 +153,37 @@ KP.1: # Inherits from JN.1 representative: England/CLIMB-CM7YEN1U/2024 reversions: [ T17334G # Reversion of JN.1.11.1 mutation, email from FedeGueli ] KP.3.1.1: # Inherits from JN.1 representative: England/CLIMB-CM7YJCHG/2024 reversions: [ C22926T, # https://github.com/sars-cov-2-variants/lineage-proposals/issues/1914 C22928T, # '' # Others I noticed while looking at the above: G7842A, T23948G, C3565T, T17334G, G19722A, G23055A, T28271A, T23063A, G22910A ] +RE.1.1: + # No inheritance -- BA.3.2 descendant with lots of dropout in Australia/WA sequences + # https://github.com/sars-cov-2-variants/lineage-proposals/issues/3093#issuecomment-3508425340 + representative: Australia/WA17392/2025 + reversions: [ A336G, C13375T, C22629A, T28996A ] + sites: [ 28254 ] + BA.4: # BA.4 is placed on the BA.2 branch so it inherits all the BA.2 sites. representative: SouthAfrica/NICD-N41664/2022 ranges: [ [ 686, 694 ], [ 21765, 21770 ] ] BA.5: # BA.5 is placed on the BA.2 branch so it inherits all the BA.2 sites. representative: England/PHEP-YYFJPAM/2022 ranges: [ [ 21765, 21770 ] ] # Some of these should be reverted in recombinants, but we're pretty much past the point of # simultaneous Delta/Omicron and the noise from false reversions is so intolerable that we'll # just have to watch out for missing reversions when working with recombinants. # False muts in recombinants that were later re-placed in BA.2.75: # XBD: G12160A, T22917G, T23018G # XBP: G12160A,