88094bfcf5dbf48fbc8147f8b457b334e3025d9b gperez2 Tue Mar 10 16:43:41 2026 -0700 Updating the DNA Methylation superTrack track description and adding the yLineOnOff setting for the Human Methylation Atlas Signals track, refs #36826 diff --git src/hg/makeDb/trackDb/human/dnaMethylation.html src/hg/makeDb/trackDb/human/dnaMethylation.html index c3983d5ed0b..615a4af7322 100644 --- src/hg/makeDb/trackDb/human/dnaMethylation.html +++ src/hg/makeDb/trackDb/human/dnaMethylation.html @@ -1,30 +1,32 @@ <h2>Description</h2> <p> This container comprises various DNA Methylation tracks from different sources. Click on the specific subtracks for detailed descriptions of the data.</p> <p> The two tracks available are: </p> <ul> <li><b>Human Methylation Atlas Summary (hg38/hg19)</b> - Contains cell-type-specific marker regions - identified from the atlas, including uniquely unmethylated loci and putative enhancer - regions annotated with regulatory features.</li> - <li><b>Human Methylation Atlas Signals (hg38/hg19)</b> - Contains per-cell-type methylation signal - tracks (bigWig format) showing methylation beta values (0-1 scale) across the genome, - with merged tracks for each cell type and individual sample replicates.</li> + identified from the atlas, including all unmethylated regions, putative + enhancers derived from unmethylated regions, and the top 250 most specifically + unmethylated regions per cell type.</li> + <li><b>Human Methylation Atlas Signals (hg38/hg19)</b> - Contains per-cell-type + methylation signal tracks (bigWig format) showing methylation beta values (0-1 scale) + across the genome, with merged tracks combining all replicates per cell type and + replicate tracks for each individual sample.</li> </ul> <h2>References</h2> <p> Loyfer N, Magenheim J, Peretz A, Cann G, Bredno J, Klochendler A, Fox-Fisher I, Shabi-Porat S, Hecht M, Pelet T <em>et al</em>. <a href="https://www.nature.com/articles/s41586-022-05580-6" target="_blank"> A DNA methylation atlas of normal human cell types</a>. <em>Nature</em>. 2023 Jan;613(7943):355-364. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/36599988" target="_blank">36599988</a> </p> <p> Loyfer N, Rosenski J, Kaplan T. <a href="https://doi.org/10.26508/lsa.202503514" target="_blank">