52ebb985f6e3658f463e971b7acd4c3959d36f92 gperez2 Wed Apr 22 17:38:06 2026 -0700 Enlarged classification diagram (40% to 60%) on the cCRE registry and Core Collection description pages. Updated the shortLabels on all 90 Core Collection subtracks with biosample + age + assay labels. refs #37131 diff --git src/hg/makeDb/trackDb/mouse/mm10/cCREregistry.html src/hg/makeDb/trackDb/mouse/mm10/cCREregistry.html index 88defafdefa..d6c09ea03ca 100644 --- src/hg/makeDb/trackDb/mouse/mm10/cCREregistry.html +++ src/hg/makeDb/trackDb/mouse/mm10/cCREregistry.html @@ -67,31 +67,31 @@ Candidate cis-regulatory elements (cCREs) were first anchored on nucleosome-sized DNase hypersensitive sites (rDHSs) identified from DNase-seq data. These rDHSs were then annotated using ChIP-seq data for histone modifications (H3K4me3 and H3K27ac, marking promoters and enhancers, respectively) and CTCF, marking insulators. To supplement rDHS-anchored cCRE definitions, transcription factor ChIP-seq peaks were incorporated, enabling identification of cCREs even in regions of low chromatin accessibility. Although not used for anchoring, ATAC-seq data were used to assess chromatin accessibility in biosamples lacking DNase-seq. Because ATAC-seq was not standardized across all biosamples, the ATAC max-Z score is not included in the registry bigBed fields or mouseOver. Only the four core assays (DNase, H3K4me3, H3K27ac, and CTCF) are reported as max-Z scores. ATAC-seq signal tracks are available in the ENCODE4 Regulation track.

The following diagram illustrates the biochemical signal patterns used to classify each cCRE type:

-Graphic of cCRE classifications

+Graphic of cCRE classifications

Data Access

The ENCODE accession numbers of the constituent datasets at the ENCODE Portal are available from the cCRE details page.

The data in this track can be interactively explored with the Table Browser or the Data Integrator. The data can be accessed from scripts through our API, the track name is "cCREregistry".

For automated download and analysis, this annotation is stored in a bigBed file that can be downloaded from our download server.