9f25bb947c005d453ff47f8beac29dc18afde9c3 jnavarr5 Fri Mar 13 15:32:43 2026 -0700 Staging the announcement for the gnomAD coverage tracks, refs #37036 diff --git src/hg/htdocs/goldenPath/newsarch.html src/hg/htdocs/goldenPath/newsarch.html index f86cda14dbd..9b8b4f21925 100755 --- src/hg/htdocs/goldenPath/newsarch.html +++ src/hg/htdocs/goldenPath/newsarch.html @@ -52,30 +52,109 @@

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Smaller software changes are not announced here. A summary of the three-weekly release changes can be found here. For the full list of our daily code changes head to our GitHub page. Lastly, see our credits page for acknowledgments of the data we host.

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Mar. 13, 2026    gnomAD v4 Exome and v3 Genome coverage tracks for hg38

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+We are pleased to announce the release of two new coverage tracks from the +Genome Aggregation Database +(gnomAD) on the human GRCh38/hg38 assembly. These tracks are part of the +Genome Aggregation Database (gnomAD) +track collection. +

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+The gnomAD v4 Exome Coverage +track displays per-base sequencing coverage statistics derived from the gnomAD v4.0 +exome callset. Coverage was computed across all gnomAD v4 exome samples using gVCFs +produced with a 3-bin blocking scheme based on reference genotype quality +(< Q20 and ≥ Q20). Note that there is no gnomAD v4 genome coverage track because +the genome samples were unchanged from v3. The track contains the following subtracks: +

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+The gnomAD v3 Genome Coverage +track displays equivalent per-base coverage statistics computed from 71,702 gnomAD +v3.0.1 whole-genome samples, also using gVCFs and the same 3-bin quality blocking +scheme. Note that there is no gnomAD v3 exome coverage track because gnomAD v3 was a +genome-only release. The track contains the following subtracks: +

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+For both tracks, clicking on a feature opens a details page that shows calculated +sample coverage percentages across the sequence range visible in the browser window. +Coverage data files in bigWig +format are available from our +download server +in the coverage/ subdirectory, and data can also be explored interactively +using the Table Browser or +Data Integrator. +Raw data are also available directly from the gnomAD +downloads page. +

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+We would like to thank the +Genome Aggregation Database +Consortium for making the data public. We also would like to thank Max Haeussler and Jairo +Navarro Gonzalez for the creation and release of the UCSC Genome Browser tracks. +

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Feb. 24, 2026    Updates to the Genome Browser Gateway Page and Assembly Search

We are excited to announce new Recent Genomes and Connected Hub Assemblies lists on the Gateway page, along with improvements to genome assembly searching across the Genome Browser. The genome assemblies search box is now also available on other pages and tools, including BLAT, In-Silico PCR, Table Browser, LiftOver, Custom Tracks, and others.