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+ ++We are pleased to announce the release of the GENCODE Genes V48 for human +(hg38/GRCh38 & +hg19/GRCh37) +and the GENCODE Genes VM37 for mouse +(mm39/GRCm39). +The GENCODE "knownGene" V48 and VM37 gene tracks were built using a UCSC +pipeline (knownGene) and the GENCODE comprehensive gene set to generate high-quality manual +annotations merged with evidence-based automated annotations. The GENCODE "knownGene" +tracks are our default gene tracks, which have extensive associations to external sources. This +allows for additional metadata on every item as well as external links. The track description +pages contain options for configuring the display, such as showing non-coding genes, splice +variants, and pseudogenes.
++Below is a summary of the contents found in each release. For more details visit the +GENCODE site.
++
| GENCODE v48 Release Stats | |||
|---|---|---|---|
| Genes | Observed | Transcripts | Observed |
| Protein-coding genes | 19,435 | +Protein-coding transcripts | 89,843 |
| Long non-coding RNA genes | 35,901 | +- full length protein-coding | 65,024 |
| Small non-coding RNA genes | 7,563 | +- partial length protein-coding | 24,819 |
| Pseudogenes | 14,695 | +Nonsense mediated decay transcripts | 21,902 |
| Immunoglobulin/T-cell receptor gene segments | +649 | Long non-coding RNA loci transcripts | 191,076 |
| Total No of distinct translations | 65,814 | +Genes that have more than one distinct translations | 13,646 |
+
| GENCODE VM37 Release Stats | |||
|---|---|---|---|
| Genes | Observed | Transcripts | Observed |
| Protein-coding genes | 21,529 | +Protein-coding transcripts | 58,636 |
| Long non-coding RNA genes | 36,111 | +- full length protein-coding | 45,038 |
| Small non-coding RNA genes | 6,105 | +- partial length protein-coding | 13,598 |
| Pseudogenes | 13,790 | +Nonsense mediated decay transcripts | 7,247 |
| Immunoglobulin/T-cell receptor gene segments | 701 | +Long non-coding RNA loci transcripts | 155,932 |
| Total No of distinct translations | 44,964 | +Genes that have more than one distinct translations | 10,850 |
+We would like to thank the GENCODE project for providing these +annotations. We would also like to thank Jonathan Casper and Jairo Navarro Gonzalez for the +development and release of these tracks.
+We are pleased to share our latest Recommended Track Set (RTS), Exon Relevance, and a new track, gnomAD Proportion Expression Across Transcript Scores (pext) for GRCh38/hg38.
The Exon Relevance track set can be found in the blue bar menu (Genome Browser > Recommended Track Sets) on both the hg19 and hg38 browsers. This track set can assist in variant interpretation by evaluating if the variant is present in an exon required for function of the expressed gene product.