This track shows genomic locations for variants in the CIViC (Clinical Interpretation of Variants in Cancer) database. These clinically -relevant variant interpretations are expert- and crowd-sourced from +relevant variant interpretations are expert and crowd-sourced from peer-reviewed literature, clinical trials, and some conference abstracts.
Each variant's interpretation is in the context of a broader molecular profile: one or more variants grouped together. For example, clinical evidence may be relevant to a KRAS G12 mutation on its own, but other clinical evidence may relevant for cases with either a mutation in KRAS G12 or G13.
The primary points of data from the scientific literature are curated as Clinical Evidence, which connects to a molecular profile, which in