b9529a41ea64f905aced9a54e8eb527c4ad490cf jnavarr5 Fri Sep 25 14:59:00 2026 -0700 Adding more missing commas, refs #38112 diff --git src/hg/makeDb/trackDb/human/hg38/episignatures.html src/hg/makeDb/trackDb/human/hg38/episignatures.html index e6b0c1ea630..f480b68b283 100644 --- src/hg/makeDb/trackDb/human/hg38/episignatures.html +++ src/hg/makeDb/trackDb/human/hg38/episignatures.html @@ -1,43 +1,43 @@
-Many rare developmental disorders are caused by variants in genes that write, read or erase +Many rare developmental disorders are caused by variants in genes that write, read, or erase DNA methylation, and such a variant leaves a reproducible pattern of altered methylation across the genome of the affected person. A pattern of this kind is called an episignature, and because it can be measured in a blood sample it is used in diagnostics to decide whether a variant of uncertain significance is really the cause of a patient's condition.
This collection holds the CpG positions that published episignatures are built from. It currently contains two tracks:
| Track | Description |
|---|---|
| MethaDory | CpG probes of the published episignatures compiled for the MethaDory classifier, covering more than 100 disorders from 74 studies |
| EpigenCentral | CpG probes of the 24 episignatures curated by the EpigenCentral portal, covering 23 disorders |
The two sets were compiled independently and overlap heavily but neither contains the other, -so a CpG site can appear in one, the other or both. +so a CpG site can appear in one, the other, or both.
Each track in this collection can be configured separately. See the description page of the -individual track for its colors, filters and item details. +individual track for its colors, filters, and item details.
The description page of each track in this collection explains how to download the underlying file and how to intersect it with other annotations.