198c9b8daecc44fbda6a6494c566c723920f030a lrnassar Wed Mar 11 18:25:21 2026 -0700 Fixing a few hundred clear typos with the help of Claude. Some are less important in code comments, but majority of them are in user-facing places. I manually approved 60%+ of the changes and didn't see any that were an incorrect suggestion, at worst it was potentially uncessesary, like a code comment having cant instead of can't. No RM. diff --git src/hg/htdocs/goldenPath/help/bigGenePred.html src/hg/htdocs/goldenPath/help/bigGenePred.html index 603afa3a5f2..1695e8f97a1 100755 --- src/hg/htdocs/goldenPath/help/bigGenePred.html +++ src/hg/htdocs/goldenPath/help/bigGenePred.html @@ -220,67 +220,67 @@ Run the bedToBigBed utility to create the bigGenePred output file (step 4, above):
bedToBigBed -type=bed12+8 -tab -as=bigGenePred.as bigGenePred.txt hg38.chrom.sizes bigGenePred.bb
  • Place the newly created bigGenePred file (bigGenePred.bb) on a web-accessible server (Step 5, above).
  • Construct a track line that points to the bigGenePred file (Step 6, above).
  • Create the custom track on the human assembly hg38 (Dec. 2013), and view it in the Genome Browser (step 7, above).
  • Example #4: GTF (or GFF) to BigGenePred

    In this example, you will convert a GTF file to bigGenePred using command line utilities. -You will need gtfToGenePred, genePredTobigGenePred, +You will need gtfToGenePred, genePredToBigGenePred, and bedToBigBed. If you would like to convert a GFF file to bigGenePred, you will use gff3ToGenePred in place of the gtfToGenePred. You can download utilities from the utilities directory.

    1. Obtain a GTF file using the wget command. Skip this step if you already have a GTF or GFF file.
      wget http://genome.ucsc.edu/goldenPath/help/examples/bigGenePredExample4.gtf
    2. Convert the GTF file to genePred extended format using the gtfToGenePred command.
      gtfToGenePred -genePredExt bigGenePredExample4.gtf example4.genePred
      If you are converting a GFF file, use the gff3ToGenePred command.
      gff3ToGenePred yourFile.gff example4.genePred 
    3. Convert the genePred extended file to a pre-bigGenePred text file.
      genePredToBigGenePred example4.genePred bigGenePredEx4.txt
    4. Download a helper file that specifies column names.
      wget https://genome.ucsc.edu/goldenPath/help/examples/bigGenePred.as
    5. Convert your text bigGenePred to a binary indexed format. If you are not using hg38, you will need to replace the hg38.chrom.sizes file path with your organism's file path from the downloads directory under "Genome Sequence Files".
      bedToBigBed -type=bed12+8 -tab -as=bigGenePred.as bigGenePredEx4.txt http://hgdownload.gi.ucsc.edu/goldenPath/hg38/bigZips/hg38.chrom.sizes bigGenePredEx4.bb
    6. Put your binary indexed file, bigGenePredEx4.bb, in a web-accessible location. See the hosting section for more information.
    7. - To view this example, you can click this into this Browser link. To view your own data, paste the + To view this example, you can click into this Browser link. To view your own data, paste the link into your web browser and replace the URL after "bigDataUrl=" with a link to your own hosted data.
       http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg38&position=chr19:44905790-44909388&hgct_customText=track%20type=bigGenePred%20bigDataUrl=http://genome.ucsc.edu/goldenPath/help/examples/bigGenePredEx4.bb
      You can also add your data in the custom track management page. This allows you to set position, configuration options, and write a more complete -desciption. If you want to see codons, you can right click, then click configure codon view or +description. If you want to see codons, you can right click, then click configure codon view or set this options using baseColorDefault=genomicCodons as is done below.
      browser position chr19:44905790-44909388 
       track type=bigGenePred baseColorDefault=genomicCodons name="bigGenePred Example Four" description="Ex4:BigGenePred Made from GTF" visibility=pack bigDataUrl=http://genome.ucsc.edu/goldenPath/help/examples/bigGenePredEx4.bb
      Once you are done, you should have a track on the Genome Browser like the one below.

    An image of a bigGenePred track on the Browser

    Example #5: Create a BigGenePred Track Hub

    In this example, you will set up a Track Hub that displays bigGenePred data and uses one of the bigGenePred-specific settings to display gene codons. You can see a pre-built version of this hub by clicking this link.

    @@ -302,31 +302,31 @@
    --hub.txt
    --genomes.txt
    --hg38
    ----trackDb.txt
    ----bigGenePred.bb
    You may also include a hub description page and a track description page, where you will find additional instructions.
  • Copy the URL address of your hub.txt file and paste it into the text input box on the Track Hub page. For an example, you can paste the following link into the input box: http://genome.ucsc.edu/goldenPath/help/examples/hubExamples/hubBigGenePred/hub.txt. -Clicking the button will connect to your track hub and navagate you to +Clicking the button will connect to your track hub and navigate you to your assembly of interest. For more instructions on setting up Track Hubs, visit the Track Hub set-up page.
  • An image of a bigGenePred track hub on the Browser

    Sharing your data with others

    If you would like to share your bigGenePred data track with a colleague, learn how to create a URL link to your data by looking at Example #6 on the custom track help page.

    Extracting data from bigBed format

    Because the bigGenePred files are an extension of bigBed files, which are indexed binary files, it