198c9b8daecc44fbda6a6494c566c723920f030a lrnassar Wed Mar 11 18:25:21 2026 -0700 Fixing a few hundred clear typos with the help of Claude. Some are less important in code comments, but majority of them are in user-facing places. I manually approved 60%+ of the changes and didn't see any that were an incorrect suggestion, at worst it was potentially uncessesary, like a code comment having cant instead of can't. No RM. diff --git src/hg/makeDb/trackDb/human/encodeUncFaire.html src/hg/makeDb/trackDb/human/encodeUncFaire.html index 482520aa6b6..0bd53c81f38 100644 --- src/hg/makeDb/trackDb/human/encodeUncFaire.html +++ src/hg/makeDb/trackDb/human/encodeUncFaire.html @@ -38,31 +38,31 @@ one subtrack, uncheck the box next to the track you wish to hide. For more information about the graphical configuration options, click the <A HREF="../goldenPath/help/hgWiggleTrackHelp.html" TARGET=_blank>Graph configuration help</A> link. Note that the graphical configuration options are available only for the Signal subtrack; the Peaks subtracks are fixed. </P> <H2>Methods</H2> <P> To perform FAIRE, proteins were cross-linked to DNA using 1% formaldehyde solution, the complex was sheared using sonication, and a phenol/chloroform extraction was performed to remove DNA fragments crosslinked to protein. The DNA recovered in the aqueous phase was fluorescently-labeled and hybridized to a microarray along with fluorescently-labeled genomic DNA as a control. Ratios were scaled by subtracting the Tukey Bi-weight mean for the log-ratio values from each -log-ratio value, as recomended by NimbleGen. Results in yeast were +log-ratio value, as recommended by NimbleGen. Results in yeast were consistent with enrichment for nucleosome-depleted regions of the genome. Therefore, the method may have utility as a positive selection for genomic regions with properties normally detected by assays like DNAse hypersensitivity. </P> <H2>Verification</H2> <P> The data were verified using PCR with primers designed to promoters enriched with FAIRE and downstream coding regions. </P> <H2>Credits</H2> <P> Cell culture, fixing, and DNA amplification were performed by Jonghwan Kim in the <A HREF="http://microarray.icmb.utexas.edu/" TARGET=_blank>Vishy Iyer lab</A> at the University of Texas, Austin. FAIRE was done by Paul Giresi in