198c9b8daecc44fbda6a6494c566c723920f030a lrnassar Wed Mar 11 18:25:21 2026 -0700 Fixing a few hundred clear typos with the help of Claude. Some are less important in code comments, but majority of them are in user-facing places. I manually approved 60%+ of the changes and didn't see any that were an incorrect suggestion, at worst it was potentially uncessesary, like a code comment having cant instead of can't. No RM. diff --git src/hg/makeDb/trackDb/human/hg38/encodeCcreCombined.html src/hg/makeDb/trackDb/human/hg38/encodeCcreCombined.html index 37f9f6b8038..e73ae1e93c3 100644 --- src/hg/makeDb/trackDb/human/hg38/encodeCcreCombined.html +++ src/hg/makeDb/trackDb/human/hg38/encodeCcreCombined.html @@ -58,31 +58,31 @@ <td>DNase-H3K4me3</td> <td>DNase-H3K4me3</td></tr> <tr><td style='background-color: #00B0F0;'</td><td>blue</td> <td>CTCF</td> <td>CTCF-only</td> <td>CTCF-only</td></tr> </table> </p> <p> The DNase-H3K4me3 elements are those with promoter-like biochemical signature that are not within 200bp of an annotated TSS. </p> <h2>Methods</h2> <p> -All individual DNase hypsersensitive sites (DHSs) identified from 706 DNase-seq experiments +All individual DNase hypersensitive sites (DHSs) identified from 706 DNase-seq experiments in humans (a total of 93 million sites from 706 experiments) were iteratively clustered and filtered for the highest signal across all experiments, producing representative DHSs (rDHSs), with a total of 2.2 million such sites in human. The highest signal elements from this set that were also supported by high H3K4me3, H3K27ac and/or CTCF ChIP-seq signals were designated cCRE's (a total of 926,535 in human). </p> <p> Classification of cCRE's was performed based on the following criteria: <ol> <li>cCREs with promoter-like signatures (cCRE-PLS) fall within 200 bp of an annotated GENCODE TSS and have high DNase and H3K4me3 signals.</li> <li>cCREs with enhancer-like signatures (cCRE-ELS) have high DNase and H3K27ac with low H3K4me3 max-Z score if they are within 200 bp of an annotated TSS. The subset of cCREs-ELS within 2 kb of a TSS is denoted proximal (cCRE-pELS), while the remaining subset is denoted distal (cCRE-dELS).</li>