10f0f6d5160a96867ecf534e1b9d138df7d9b796 lrnassar Mon Sep 28 16:17:46 2026 -0700 Fiber-seq: hide the container by default, and split the five GM lines out into a Rare disease sample class. Max asked for superTrack on rather than on show, since the track covers much the same ground as ENCODE DNase and does not earn a slot in everyone's default hg38 view. The five lymphoblastoid lines GM25455, GM25456, GM27730, GM28570 and GM28572 had been filed as Common Cell Line; Andrew Stergachis says they are rare disease cases consented to broad genomic data sharing and the first of a batch the lab intends to keep adding, so SAMPLE_CLASS_COLORS gains a third entry and the facet now reads 20 HPRC, 16 Common Cell Line, 5 Rare disease sample. refs #36210 diff --git src/hg/makeDb/trackDb/human/hg38/fiberSeq.html src/hg/makeDb/trackDb/human/hg38/fiberSeq.html index be3ff652f1c..b4d63ba5c63 100644 --- src/hg/makeDb/trackDb/human/hg38/fiberSeq.html +++ src/hg/makeDb/trackDb/human/hg38/fiberSeq.html @@ -8,32 +8,32 @@ sequence, the added adenine methylation and the native CpG methylation from the same molecule. Because the reads are long enough to span heterozygous variants, they can be phased to a parental haplotype, giving a chromatin picture for each allele separately rather than an average of the two. </p> <p> The accessibility this measures is the same property that DNase-seq and ATAC-seq measure, and the tracks here can be read much as those are. The difference is that Fiber-seq reports it one molecule at a time, so a value is a fraction of molecules rather than a pile of cut sites, and it can be split by haplotype. </p> <p> This collection holds the Fiber-seq data from the Stergachis and Vollger labs for 41 samples, -covering common cell lines and 20 lymphoblastoid lines from individuals sequenced by the Human -Pangenome Reference Consortium. It contains two tracks: +covering common cell lines, 20 lymphoblastoid lines from individuals sequenced by the Human +Pangenome Reference Consortium, and five rare disease cases. It contains two tracks: </p> <ul> <li><a href="hgTrackUi?db=hg38&g=fiberSeqAcc">Fiber-seq Acc</a> shows percent-accessible chromatin for seven widely used cell lines as a single overlay, so accessibility can be compared across cell types at a glance.</li> <li><a href="hgTrackUi?db=hg38&g=fiberSeqCompendium">Fiber-seq Compendium</a> holds everything, for every one of the 41 samples: the percent-accessible signal, the called FIRE regulatory element peaks, CpG methylation, and per-haplotype versions of the accessibility and the methylation. Samples are selected from a searchable table.</li> </ul> <p> Related data can be found in the <a href="hgTrackUi?db=hg38&g=dnaMethylation">DNA Methylation</a> collection, which holds methylation measured by other assays.