53ab3f1e293a91ddf71ec7568f4a6ff827bcd278 lrnassar Fri Oct 2 13:52:36 2026 -0700 Native GPN-Star track (Ye, Benegas et al., Nature 2026) on hg38, mm39, galGal6, dm6 and ce11, from the authors' Hugging Face hub. Each model is a multiWig sequence logo plus a four-allele -LLR composite using negateValues. The three hg38 models (V/M/P) sit in predictionScoresSuper via human/gpnStar.ra with /gbdb/$D bigDataUrls so -strict drops them on other human assemblies; the other four get a standalone gpnStar superTrack. The authors' bigWigs come from pyBigWig, whose bwAddIntervalSpanSteps writes the last section of each run 6 bases too long (pyBigWig #166) and makes bigWigAverageOverBed and bigWigCorrelate abort, so gpnStarRebuild.sh re-encodes them with wigToBigWig and gpnStarVerify.sh checks every per-base value is unchanged. Entropy scores and the GenArk-only Arabidopsis set are left out, and pennantIcon still has #TBD placeholders for the newsarch anchor and date. refs #38451 diff --git src/hg/makeDb/trackDb/mouse/mm39/gpnStar.ra src/hg/makeDb/trackDb/mouse/mm39/gpnStar.ra new file mode 100644 index 00000000000..362f8defb91 --- /dev/null +++ src/hg/makeDb/trackDb/mouse/mm39/gpnStar.ra @@ -0,0 +1,125 @@ +track gpnStar +shortLabel GPN-Star +longLabel GPN-Star genomic language model constraint scores (35 vertebrates) +superTrack on +pennantIcon New red ../goldenPath/newsarch.html#TBD "Released TBD" +dataVersion GPN-Star scores, Hugging Face revision 47e7f05 (September 2026) +group compGeno + +track gpnStarLogo +shortLabel GPN-Star Logo +longLabel GPN-Star (35 vertebrates) sequence logo of predicted constraint +parent gpnStar +container multiWig +html gpnStar +maxWindowToDraw 10000000 +mouseOverFunction noAverage +dataVersion GPN-Star scores, Hugging Face revision 47e7f05 (September 2026) +type bigWig 0 2 +aggregate stacked +logo on +showSubtrackColorOnUi on +autoScale off +viewLimits 0:2 +viewLimitsMax 0:2 +maxHeightPixels 100:40:16 +visibility full + + track gpnStarLogoA + shortLabel A + longLabel GPN-Star (35 vertebrates) logo height of A + parent gpnStarLogo + type bigWig 0 2 + bigDataUrl /gbdb/mm39/gpnStar/A.bw + color 0,128,0 + priority 1 + + track gpnStarLogoC + shortLabel C + longLabel GPN-Star (35 vertebrates) logo height of C + parent gpnStarLogo + type bigWig 0 2 + bigDataUrl /gbdb/mm39/gpnStar/C.bw + color 0,0,255 + priority 2 + + track gpnStarLogoG + shortLabel G + longLabel GPN-Star (35 vertebrates) logo height of G + parent gpnStarLogo + type bigWig 0 2 + bigDataUrl /gbdb/mm39/gpnStar/G.bw + color 255,166,0 + priority 3 + + track gpnStarLogoT + shortLabel T + longLabel GPN-Star (35 vertebrates) logo height of T + parent gpnStarLogo + type bigWig 0 2 + bigDataUrl /gbdb/mm39/gpnStar/T.bw + color 255,0,0 + priority 4 + +track gpnStarLlr +shortLabel GPN-Star -LLR +longLabel GPN-Star (35 vertebrates) -LLR per alternate allele +parent gpnStar +compositeTrack on +html gpnStar +maxWindowToDraw 10000000 +mouseOverFunction noAverage +dataVersion GPN-Star scores, Hugging Face revision 47e7f05 (September 2026) +type bigWig +autoScale off +alwaysZero on +viewLimits -3:10 +viewLimitsMax -16:16 +negateValues on +yLineOnOff on +yLineMark 0 +graphTypeDefault bar +maxHeightPixels 100:16:16 +windowingFunction mean+whiskers +visibility dense + + track gpnStarLlrA + shortLabel Mutation: A + longLabel GPN-Star (35 vertebrates) -LLR: Mutation is A + parent gpnStarLlr on + type bigWig + bigDataUrl /gbdb/mm39/gpnStar/llr_A.bw + color 140,60,60 + altColor 60,60,140 + priority 1 + + track gpnStarLlrC + shortLabel Mutation: C + longLabel GPN-Star (35 vertebrates) -LLR: Mutation is C + parent gpnStarLlr on + type bigWig + bigDataUrl /gbdb/mm39/gpnStar/llr_C.bw + color 140,60,60 + altColor 60,60,140 + priority 2 + + track gpnStarLlrG + shortLabel Mutation: G + longLabel GPN-Star (35 vertebrates) -LLR: Mutation is G + parent gpnStarLlr on + type bigWig + bigDataUrl /gbdb/mm39/gpnStar/llr_G.bw + color 140,60,60 + altColor 60,60,140 + priority 3 + + track gpnStarLlrT + shortLabel Mutation: T + longLabel GPN-Star (35 vertebrates) -LLR: Mutation is T + parent gpnStarLlr on + type bigWig + bigDataUrl /gbdb/mm39/gpnStar/llr_T.bw + color 140,60,60 + altColor 60,60,140 + priority 4 +