b197e1670a076b65838fd91b869a4ec1c3096c0f
max
  Wed Sep 23 16:08:08 2026 -0700
Add Panmask Difficult 151b, the inverse of Panmask Easy 151b, for the Problematic Regions RTS

Panmask marks easy regions under a "Problematic Regions" container, which Anna
flagged as confusing. Rather than change the released Panmask Easy track, add
a second track with the complement regions, built with featureBits (excluding
assembly gaps and restricted to the 24 chromosomes Panmask itself covers).
Checked the source first: Zenodo record 16755940 is still v1.4, same version
already in use, MD5 verified. New track is alpha only for QA to pick up.

refs #38375

diff --git src/hg/makeDb/trackDb/human/hg38/problematic.ra src/hg/makeDb/trackDb/human/hg38/problematic.ra
index e538ab528dc..b1b0b2a5444 100644
--- src/hg/makeDb/trackDb/human/hg38/problematic.ra
+++ src/hg/makeDb/trackDb/human/hg38/problematic.ra
@@ -178,20 +178,31 @@
         shortLabel Not lowMap+SegDup
         longLabel Genome In a Bottle: not lowMap+SegDup mapping regions
         type bigBed 3
         visibility dense
 
     track panmask151b
     parent problematicSuper on
     bigDataUrl /gbdb/hg38/problematic/hg38.pm151b-v3.easy.bb
     shortLabel Panmask Easy 151b
     longLabel Panmask Easy 151b Regions: High accuracy for variant calling
     type bigBed 3
     dataVersion pm151b-v3.easy.bed.gz (Panmask v1.4, Aug 6 2025, MD5: 2f59a43dab0b463bafcf3b59fc62)
     visibility hide
     html problematic
 
+    track panmask151bDifficult
+    parent problematicSuper on
+    release alpha
+    bigDataUrl /gbdb/hg38/problematic/hg38.pm151b-v3.notEasy.bb
+    shortLabel Panmask Difficult 151b
+    longLabel Panmask Difficult 151b Regions: Lower accuracy for variant calling, inverse of Panmask Easy
+    type bigBed 3
+    dataVersion Inverse of pm151b-v3.easy.bed.gz (Panmask v1.4, Aug 6 2025), computed with featureBits
+    visibility hide
+    html problematic
+
 searchTable comments
 searchPriority 0.5
 searchType bigBed
 searchDescription Special genome loci: gene clusters, haplotypes, patches, etc.