f30798ae5d11e88e0ab7eb2bcab634e253fd0675
max
  Thu Apr 23 10:36:40 2026 -0700
Add gnomAD MPC v4.1.1 track to hg38.

New composite track under the gnomAD container showing per-variant
MPC (Missense deleteriousness Prediction by Constraint) scores from
gnomAD v4.1.1. Four bigWigs provide per-base scores (one per ALT
nucleotide); a companion bigBed carries the ~250K multi-transcript
variants with a per-transcript breakdown. Included via 'alpha' for
QA review. refs #37434

Co-Authored-By: Claude Opus 4.7 (1M context) <noreply@anthropic.com>

diff --git src/hg/makeDb/trackDb/human/hg38/trackDb.ra src/hg/makeDb/trackDb/human/hg38/trackDb.ra
index 82dd873ee82..e6a1bac8849 100644
--- src/hg/makeDb/trackDb/human/hg38/trackDb.ra
+++ src/hg/makeDb/trackDb/human/hg38/trackDb.ra
@@ -676,30 +676,31 @@
 
 # ENCODE tracks
 
 include trackDb.gencode.ra
 
 include wgEncodeReg.ra beta,public
 include wgEncodeReg.alpha.ra alpha
 include wgEncodeReg4.ra alpha
 
 include encode3.ra
 include encode.cCREs.override.ra
 
 include hic.ra
 
 include gnomad.ra
+include gnomadMpc.ra alpha
 
 
 include platinumGenomes.ra
 
 track epdNew
 compositeTrack on
 shortLabel EPDnew Promoters
 longLabel Promoters from EPDnew
 html ../../epdNewPromoter
 type bigBed 8
 group expression
 visibility hide
 urlLabel EPDnew link:
 bedNameLabel Promoter ID
 exonArrows on