e82a8101c1aa495e0e6c841f83f4d6c980fddf49
max
  Thu Mar 12 07:28:49 2026 -0700
Add STRchive disease-associated STR loci track to strVar supertrack

75 curated disease-associated tandem repeat expansion loci from
STRchive (Hiatt et al. 2025), with pathogenic thresholds, inheritance
modes, and disease annotations. Colored by inheritance mode, refs #36652

Co-Authored-By: Claude Opus 4.6 <noreply@anthropic.com>

diff --git src/hg/makeDb/scripts/strchive/strchive.as src/hg/makeDb/scripts/strchive/strchive.as
new file mode 100644
index 00000000000..8bcc0ee67ed
--- /dev/null
+++ src/hg/makeDb/scripts/strchive/strchive.as
@@ -0,0 +1,19 @@
+table strchive
+"STRchive disease-associated short tandem repeat loci"
+    (
+    string chrom;              "Chromosome"
+    uint chromStart;           "Start position"
+    uint chromEnd;             "End position"
+    string name;               "Locus ID (disease_gene)"
+    uint score;                "Score (0-1000)"
+    char[1] strand;            "Strand"
+    uint thickStart;           "Thick start (same as chromStart)"
+    uint thickEnd;             "Thick end (same as chromEnd)"
+    uint reserved;             "Item color RGB"
+    string gene;               "Gene symbol"
+    string referenceMotif;     "Repeat motif in reference orientation"
+    string pathogenicMotif;    "Pathogenic repeat motif"
+    string pathogenicMin;      "Minimum pathogenic repeat count"
+    string inheritance;        "Mode of inheritance"
+    lstring disease;           "Associated disease(s)"
+    )