e82a8101c1aa495e0e6c841f83f4d6c980fddf49
max
  Thu Mar 12 07:28:49 2026 -0700
Add STRchive disease-associated STR loci track to strVar supertrack

75 curated disease-associated tandem repeat expansion loci from
STRchive (Hiatt et al. 2025), with pathogenic thresholds, inheritance
modes, and disease annotations. Colored by inheritance mode, refs #36652

Co-Authored-By: Claude Opus 4.6 <noreply@anthropic.com>

diff --git src/hg/makeDb/trackDb/human/hg38/webstr.ra src/hg/makeDb/trackDb/human/hg38/webstr.ra
index 379cebfd905..743282d177e 100644
--- src/hg/makeDb/trackDb/human/hg38/webstr.ra
+++ src/hg/makeDb/trackDb/human/hg38/webstr.ra
@@ -1,21 +1,35 @@
 track strVar
 shortLabel STR Variation
 longLabel Short Tandem Repeat Variation
 group varRep
 superTrack on
 html strVar.html
 visibility hide
 
     track webstr
     shortLabel WebSTR
     longLabel WebSTR Short Tandem Repeat Loci (EnsembleTR Panel, 1000 Genomes)
     type bigBed 9 +
     itemRgb on
     bigDataUrl /gbdb/hg38/webstr/webstr.bb
     visibility dense
     superTrack strVar dense
     url https://webstr.ucsd.edu/locus?repeat_id=$$&genome=hg38
     urlLabel WebSTR locus page
     searchIndex name
     mouseOver $motif repeat, $numCopies copies, period $period
     html webstr.html
+
+    track strchive
+    shortLabel STRchive
+    longLabel STRchive Disease-Associated Short Tandem Repeat Loci
+    type bigBed 9 +
+    itemRgb on
+    bigDataUrl /gbdb/hg38/webstr/strchive.bb
+    visibility pack
+    superTrack strVar pack
+    url https://strchive.org/loci/$$
+    urlLabel STRchive locus page
+    searchIndex name
+    mouseOver $name: $referenceMotif repeat in $gene, pathogenic min $pathogenicMin ($inheritance)
+    html strchive.html