cf9cfcd463d40a868f8ee73dead17ff8071dce2f
max
  Fri Sep 25 03:00:20 2026 -0700
CRISPR tracks: expose colorFields dropdown to color guides by off-target
specificity (MIT score) or by Moreno-Mateos efficiency, as alternatives to
the default Doench/Fusi-based itemRgb color. The bigBed already carries
these as the _specColor and _crisprScanColor extra fields; no data rebuild
needed.

diff --git src/hg/makeDb/trackDb/human/hs1/crispr.ra src/hg/makeDb/trackDb/human/hs1/crispr.ra
index 0ddffb2aff9..839cd5133e9 100644
--- src/hg/makeDb/trackDb/human/hs1/crispr.ra
+++ src/hg/makeDb/trackDb/human/hs1/crispr.ra
@@ -1,19 +1,20 @@
 track crisprHs1
 visibility hide
 shortLabel CRISPR Targets
 longLabel CRISPR/Cas9 -NGG Targets, whole genome
 group genes
 type bigBed 9 +
 html crisprAll
 itemRgb on
 mouseOverField _mouseOver
 scoreLabel MIT Guide Specificity Score
 bigDataUrl /gbdb/hs1/crispr/crispr.bb
 # details page is not using a mysql table but a tab-sep file
 detailsTabUrls _offset=/gbdb/hs1/crispr/crisprDetails.tab
 url http://crispor.gi.ucsc.edu/crispor.py?org=$D&pos=$S:${&pam=NGG
 urlLabel Click here to show this guide on Crispor.org, with expression oligos, validation primers and more
 tableBrowser tbNoGenome
 noGenomeReason This track is too big for whole-genome Table Browser access, it would lead to a timeout in your internet browser. Small regional queries can work, but large regions, such as entire chromosomes, will fail. Please see the CRISPR Track documentation, the section "Data Access", for bulk-download options and remote access via the bedToBigBed tool. API access should always work. Contact us if you encounter difficulties with accessing the data.
 denseCoverage 0
 scoreFilterMax 100
+colorFields default="Efficiency (Doench/Fusi)" _specColor="Off-target specificity (MIT score)" _crisprScanColor="Efficiency (Moreno-Mateos)"