59fb440ba930a3f0eaee0af6e7fe6a2526b10551
gperez2
  Wed Dec 3 11:49:31 2025 -0800
More updates to gnomadMpc.html and releasing/announcing the hg19 gnomAD MPC track, refs #36531

diff --git src/hg/makeDb/trackDb/human/hg19/gnomadMpc.html src/hg/makeDb/trackDb/human/hg19/gnomadMpc.html
index 87e28e4dc07..7e5f3fa4688 100644
--- src/hg/makeDb/trackDb/human/hg19/gnomadMpc.html
+++ src/hg/makeDb/trackDb/human/hg19/gnomadMpc.html
@@ -1,31 +1,31 @@
 <h2>Description</h2>
 <p>
 The <b>${longLabel}</b> track shows a score that tries to identify missense-depleted
 regions using the patterns of rare missense variation in 125,748 gnomAD v2.1.1 exomes,
 compared to a null mutational model. Missense-depleted regions are enriched for ClinVar pathogenic
 variants, de novo missense variants in individuals with neurodevelopmental disorders (NDDs), and
 complex trait heritability. The score's publication suggests that regions
 with less than 20% of their expected missense variation achieve moderate
 support for pathogenicity according to ACMG criteria.
 </p>
 
 <h2>Display Conventions and Configuration</h2>
 
 <p>
-Regions of transcripts with constraint predictions are colored using the viridis palette, where
-yellow indicates the lowest OE values and dark blue-purple indicates the highest.
+Transcript regions with constraint predictions are colored using the viridis palette, where yellow
+indicates the lowest OE values and dark blue-purple indicates the highest.
 </p>
 
 <p><strong>OE Constraint Legend</strong><br>
 Yellow = strongest constraint<br>
 Purple = weakest constraint
 </p>
 <table>
   <thead>
   <tr>
     <th style="border-bottom: 2px solid #6678B1;">Color</th>
     <th style="border-bottom: 2px solid #6678B1;">OE Range</th>
   </tr>
   </thead>
     <tr>
         <th bgcolor="#FDE724"></th>
@@ -122,29 +122,28 @@
 <p>
 Please refer to our
 <A HREF="https://groups.google.com/a/soe.ucsc.edu/forum/?hl=en&fromgroups#!search/gnomAD"
 target="_blank">mailing list archives</a>
 for questions and example queries, or our
 <a HREF="../FAQ/FAQdownloads.html#download36" target="_blank">Data Access FAQ</a>
 for more information.</p>
 
 <p>
 More information about using and understanding the gnomAD data can be found on the
 <a target="_blank" href="https://gnomad.broadinstitute.org/faq">gnomAD FAQ</a> site.
 </p>
 
 <h2>Credits</h2>
 <p>
-Thanks to gnomAD for releasing this data and to Luis Nassar for finding it.
-</p>
+Thanks to Kaitlin Samocha for suggesting this track. Thanks to gnomAD for releasing the data and to
+Luis Nassar for locating it.</p>
 
 <h2>References</h2>
 <p>
 Chao KR, Wang L, Panchal R, Liao C, Abderrazzaq H, Ye R, Schultz P, Compitello J, Grant RH, Kosmicki
 JA <em>et al</em>.
 <a href="https://doi.org/10.1101/2024.04.11.588920" target="_blank">
 The landscape of regional missense mutational intolerance quantified from 125,748 exomes</a>.
 <em>bioRxiv</em>. 2024 May 3;.
 PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/38645134" target="_blank">38645134</a>; PMC: <a
 href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11030311/" target="_blank">PMC11030311</a>
 </p>
-