e7627f2c8a0215940699e390bf24a17cb60fdeec
gperez2
  Sun Aug 23 22:22:01 2026 -0700
Changing the v2/v4/v4.1 constraint subtracks to hide by default. Updating the pliByTranscriptV4_1_1's mouseOver, plus some other minor updates. refs #37351

diff --git src/hg/makeDb/trackDb/human/hg38/gnomad.constraint.public.ra src/hg/makeDb/trackDb/human/hg38/gnomad.constraint.public.ra
index 45f4d4e7614..861623a7b4b 100644
--- src/hg/makeDb/trackDb/human/hg38/gnomad.constraint.public.ra
+++ src/hg/makeDb/trackDb/human/hg38/gnomad.constraint.public.ra
@@ -1,178 +1,178 @@
 track gnomadPLI
 parent gnomadVariants 
 shortLabel gnomAD Constraint Metrics
 longLabel Genome Aggregation Database (gnomAD) Predicted Constraint Metrics (LOEUF, pLI, and Z-scores)
 compositeTrack On
 group varRep
 type bigBed 12
 labelFields name,geneName
 dataVersion Release v4.1 (April 19, 2024), Release v4 (November 2023), Release 2.1.1 (March 6, 2019)
 subGroup1 view Views v2=constraintV2 v4=constraintV4 v4_1=constraintV4.1
 html gnomadPLI.html
 visibility hide
 
     track constraintV2
     parent gnomadPLI off
     shortLabel Constraint V2
     longLabel gnomAD Constraint Metrics V2
     view v2
     visibility pack
     type bigBed 12 +
 
         track pliByGene
         shortLabel Gene LoF
         longLabel gnomAD Predicted Loss of Function Constraint Metrics By Gene (LOEUF and pLI) v2.1.1
         subGroups view=v2
         type bigBed 12 +
         itemRgb on
         searchIndex name,geneName
         bigDataUrl /gbdb/hg38/gnomAD/pLI/pliByGene.bb
         url https://gnomad.broadinstitute.org/gene/$$?dataset=gnomad_r2_1
         urlLabel View this Gene on the gnomAD browser
         labelFields name,geneName
         defaultLabelFields geneName
         filter._pli 0:1
         filterLabel._pli Show only items between this pLI range
         filterByRange._pli on
-        parent constraintV2 on
+        parent constraintV2 off
         priority 1
         mouseOver LOEUF: $_loeuf<br> pLI: $_pli<br> $synonymous<br> $pLoF
 
         track missenseByGene
         shortLabel Gene Missense
         longLabel gnomAD Predicted Missense Constraint Metrics By Gene (Z-scores) v2.1.1
         subGroups view=v2
         type bigBed 12 +
         searchIndex name,geneName
         bigDataUrl /gbdb/hg38/gnomAD/pLI/missenseByGene.bb
         url https://gnomad.broadinstitute.org/gene/$$?dataset=gnomad_r2_1
         urlLabel View this Gene on the gnomAD browser
         labelFields name,geneName
         filter._zscore -19:11
         itemRgb on
         filterLabel._zscore Show only items between this Z-score range
         filterByRange._zscore on
         parent constraintV2 off
         priority 2
         mouseOver Z: $_zscore<br> $synonymous<br> $missense
 
         track pliByTranscript
         shortLabel Transcript LoF v2
         longLabel gnomAD Predicted Loss of Function Constraint Metrics By Transcript (LOEUF and pLI) v2.1.1
         subGroups view=v2
         type bigBed 12 +
         itemRgb on
         searchIndex name,geneName
         bigDataUrl /gbdb/hg38/gnomAD/pLI/pliByTranscript.bb
         url https://gnomad.broadinstitute.org/transcript/$$?dataset=gnomad_r2_1
         urlLabel View this Transcript on the gnomAD browser
         labelFields name,geneName
         filter._pli 0:1
         filterLabel._pli Show only items between this pLI range
         filterByRange._pli on
         parent constraintV2 off
         priority 2
         mouseOver LOEUF: $_loeuf<br> pLI: $_pli<br> $synonymous<br> $pLoF
 
         track missenseByTranscript
         shortLabel Transcript Missense v2
         longLabel gnomAD Predicted Missense Constraint Metrics By Transcript (Z-scores) v2.1.1
         subGroups view=v2
         type bigBed 12 +
         searchIndex name,geneName
         bigDataUrl /gbdb/hg38/gnomAD/pLI/missenseByTranscript.bb
         url https://gnomad.broadinstitute.org/transcript/$$?dataset=gnomad_r2_1
         urlLabel View this Transcript on the gnomAD browser
         labelFields name,geneName
         filter._zscore -20:11
         filterLabel._zscore Show only items between this Z-score range
         filterByRange._zscore on
         parent constraintV2 off
         priority 2
         mouseOver Z: $_zscore<br> $synonymous<br> $missense
 
     track constraintV4
     parent gnomadPLI off
     shortLabel Constraint V4
     longLabel gnomAD Constraint Metrics V4
     view v4
     visibility hide
     type bigBed 12 +
     
         track pliByTranscriptV4
         shortLabel Transcript LoF v4
         longLabel gnomAD Predicted Loss of Function Constraint Metrics By Transcript (LOEUF and pLI) v4
         subGroups view=v4
         type bigBed 12 +
         itemRgb on
         searchIndex name,geneName
         bigDataUrl /gbdb/hg38/gnomAD/pLI/pliByTranscript.v4.bb
         url https://gnomad.broadinstitute.org/transcript/$$?dataset=gnomad_r4
         urlLabel View this Transcript on the gnomAD browser
         labelFields name,geneName
         filter._pli 0:1
         filterLabel._pli Show only items between this pLI range
         filterByRange._pli on
-        parent constraintV4
+        parent constraintV4 off
         priority 2
         mouseOver LOEUF: $_loeuf<br> pLI: $_pli<br> $synonymous<br> $pLoF
 
         track missenseByTranscriptV4
         shortLabel Transcript Missense v4
         longLabel gnomAD Predicted Missense Constraint Metrics By Transcript (Z-scores) v4
         subGroups view=v4
         type bigBed 12 +
         searchIndex name,geneName
         bigDataUrl /gbdb/hg38/gnomAD/pLI/missenseByTranscript.v4.bb
         url https://gnomad.broadinstitute.org/transcript/$$?dataset=gnomad_r4
         urlLabel View this Transcript on the gnomAD browser
         labelFields name,geneName
         filter._zscore -20:11
         filterLabel._zscore Show only items between this Z-score range
         filterByRange._zscore on
-        parent constraintV4
+        parent constraintV4 off
         priority 2
         mouseOver Z: $_zscore<br> $synonymous<br> $missense
 
     track constraintV4_1
     parent gnomadPLI off
     shortLabel Constraint V4.1
     longLabel gnomAD Constraint Metrics V4.1
     view v4_1
     visibility pack
     type bigBed 12 +
 
         track pliByTranscriptV4_1
         shortLabel Transcript LoF v4.1
         longLabel gnomAD Predicted Loss of Function Constraint Metrics By Transcript (LOEUF and pLI) v4.1
         subGroups view=v4_1
         type bigBed 12 +
         itemRgb on
         searchIndex name,geneName
         bigDataUrl /gbdb/hg38/gnomAD/pLI/pliByTranscript.v4.1.bb
         url https://gnomad.broadinstitute.org/transcript/$$?dataset=gnomad_r4
         urlLabel View this Transcript on the gnomAD browser
         labelFields name,geneName
         filter._pli 0:1
         filterLabel._pli Show only items between this pLI range
         filterByRange._pli on
-        parent constraintV4_1
+        parent constraintV4_1 off
         priority 2
         mouseOver LOEUF: $_loeuf<br> pLI: $_pli<br> $synonymous<br> $pLoF
 
         track missenseByTranscriptV4_1
         shortLabel Transcript Missense v4.1
         longLabel gnomAD Predicted Missense Constraint Metrics By Transcript (Z-scores) v4.1
         subGroups view=v4_1
         type bigBed 12 +
         searchIndex name,geneName
         bigDataUrl /gbdb/hg38/gnomAD/pLI/missenseByTranscript.v4.1.bb
         url https://gnomad.broadinstitute.org/transcript/$$?dataset=gnomad_r4
         urlLabel View this Transcript on the gnomAD browser
         labelFields name,geneName
         filter._zscore -20:11
         filterLabel._zscore Show only items between this Z-score range
         filterByRange._zscore on
-        parent constraintV4_1
+        parent constraintV4_1 off
         priority 2
         mouseOver Z: $_zscore<br> $synonymous<br> $missense