+This track represents fixed retrocopies identified and annotated by +RCPedia pipeline. +Retrocopies are genomic copies generated by reverse transcription and +reintegration of processed messenger RNAs (mRNAs). Because they originate +from processed transcripts, retrocopies generally lack introns and may +retain complete or partial open reading frames from their parental genes. +
+ ++RCPedia contains more than 219,000 fixed retrocopies across 44 eukaryotic +species, providing information on genomic coordinates, parental genes, +genomic context, sequence, conservation and expression. +
+ ++Each feature represents a fixed retrocopy locus in the corresponding +reference genome. The track coordinates follow the +UCSC Genome Browser +0-based coordinate system. +
+ ++Fixed retrocopies were identified by aligning RefSeq mRNAs to reference +genomes using LAST, followed by filtering based on alignment quality, +genomic distance from the parental gene, exon-exon junctions and repetitive +sequence content. Candidate loci were further filtered to reduce false +positives arising from duplicated genes and large gene families. +
+ ++For detailed methodology, please refer to the + +RCPedia FAQ. +
+ ++RCPedia pipeline was developed by the Galante Lab and collaborators. +
+ ++For questions or additional information, please visit the + +RCPedia Contact & Credits page. +
+ ++Conceição HB, Mercuri RLV, de Castro MPM, Ohara DT, Guardia GDA, +Galante PAF. RCPedia: A global resource for studying and exploring +retrocopies in diverse species. Bioinformatics. 2024;40(9):btae530. + +doi:10.1093/bioinformatics/btae530. +