0b88e0fa63875f67aaf77a4fefc4038ee6caee58 hiram Fri Sep 11 16:09:16 2026 -0700 meat puppet here, claude didn't like the name mismatch, oh well, whatever, it isn't important what the name is here refs #38224 diff --git src/hg/makeDb/trackDb/contrib/RCPediaVGP_v1/retrocopies.html src/hg/makeDb/trackDb/contrib/RCPediaVGP_v1/retrocopies.html new file mode 100644 index 00000000000..fbd7c74560f --- /dev/null +++ src/hg/makeDb/trackDb/contrib/RCPediaVGP_v1/retrocopies.html @@ -0,0 +1,67 @@ +<h2>Description</h2> + +<p> +This track represents fixed retrocopies identified and annotated by +<a href="https://www.rcpediadb.org/" target="_blank">RCPedia pipeline</a>. +Retrocopies are genomic copies generated by reverse transcription and +reintegration of processed messenger RNAs (mRNAs). Because they originate +from processed transcripts, retrocopies generally lack introns and may +retain complete or partial open reading frames from their parental genes. +</p> + +<p> +RCPedia contains more than 219,000 fixed retrocopies across 44 eukaryotic +species, providing information on genomic coordinates, parental genes, +genomic context, sequence, conservation and expression. +</p> + +<h2>Display Conventions and Configuration</h2> + +<p> +Each feature represents a fixed retrocopy locus in the corresponding +reference genome. The track coordinates follow the +<a href="https://genome.ucsc.edu/" target="_blank">UCSC Genome Browser</a> +0-based coordinate system. +</p> + +<ul> + <li><b>Retrocopy:</b> genomic location of the fixed retrocopy.</li> +</ul> + +<h2>Methods</h2> + +<p> +Fixed retrocopies were identified by aligning RefSeq mRNAs to reference +genomes using LAST, followed by filtering based on alignment quality, +genomic distance from the parental gene, exon-exon junctions and repetitive +sequence content. Candidate loci were further filtered to reduce false +positives arising from duplicated genes and large gene families. +</p> + +<p> +For detailed methodology, please refer to the +<a href="https://www.rcpediadb.org/pages/faq" target="_blank"> +RCPedia FAQ</a>. +</p> + +<h2>Credits</h2> + +<p> +RCPedia pipeline was developed by the Galante Lab and collaborators. +</p> + +<p> +For questions or additional information, please visit the +<a href="https://www.rcpediadb.org/pages/contact" target="_blank"> +RCPedia Contact & Credits</a> page. +</p> + +<h2>References</h2> + +<p> +Conceição HB, Mercuri RLV, de Castro MPM, Ohara DT, Guardia GDA, +Galante PAF. RCPedia: A global resource for studying and exploring +retrocopies in diverse species. <i>Bioinformatics</i>. 2024;40(9):btae530. +<a href="https://doi.org/10.1093/bioinformatics/btae530" target="_blank"> +doi:10.1093/bioinformatics/btae530</a>. +</p>