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+ ++We are happy to announce the release of the Unusually Conserved Regions track for GRCh38/hg38. The supertrack consists of +12 tracks that show regions of unusual conservation in humans relative to other organisms. The full +list of tracks, along with item count and coverage is summarized in the following table: +
++
| Track | +Count | +Coverage in bp | +
|---|---|---|
| HAQERS: Human Ancestor Quickly Evolved Regions | +1,580 | +1,410,669 | +
| HARs: Human Accelerated Regions (HARs) merged from various + publications by the Pollard Lab | +2,647 | +681,420 | +
| Long hConDels: Long Human Conserved Deletions - present in chimp and + macaque but deleted in humans | +583 | +293,809 | +
| Short hConDels: Human Conserved Deletions < 40bp | +10,032 | +1,968,123 | +
| UCNEBase Chicken - Chicken-conserved elements | +4,351 | +1,415,142 | +
| UCNEBase Paralogs - Paralogous elements | +987 | +215,800 | +
| UCNEBase Clusters: Ultra-conserved genomic regulatory blocks | +239 | +199,269,634 | +
| Ultracons: Ultraconserved regions - + 100% identical in human, mouse and rat, >200bp | +481 | +126,007 | +
| UltraZoos: Ultraconserved regions in Zoonomia alignment - + 100% identical in 235 species, >20bp | +4,552 | +131,661 | +
| ZooHARs: Human Accelerated Regions (HARs) from Zoonomia alignments | +312 | +49,173 | +
| Zoonomia RoCCs: Runs of contiguous phyloP constraint | +595,536 | +26,995,284 | +
| Zoonomia UNICORNs: Unannotated Intergenic Constrained Regions | +423,586 | +16,155,520 | +
+We would like to thank Katie Pollard, Hiram Clawson, James Xue, Matt Christmas, Carol Nguyen, +and Mark Diekhans for providing the data. We would also like to thank Max Haeussler and Jairo +Navarro for the creation and release of the tracks. +
+
July 7th marks the 25th anniversary of the human genome going online, and the start of the
UCSC Genome Browser. Our visualization journey
began when Jim Kent wrote the Intronerator, which displayed regions of C. elegans. This was the
foundation for the UCSC Genome Browser as we know it now, and decades later, we are
proud to continue serving our ever-growing users.
So, how has the Browser evolved over the years?