a57e95fd50c67dfcb633c5732844d411655b07a0 jnavarr5 Fri Oct 24 15:46:37 2025 -0700 Fixing a singular-plural disconnect that Bob wrote in about, refs #36576 diff --git src/hg/makeDb/trackDb/human/hg38/mane.html src/hg/makeDb/trackDb/human/hg38/mane.html index 5db45b22a90..dbe44761652 100644 --- src/hg/makeDb/trackDb/human/hg38/mane.html +++ src/hg/makeDb/trackDb/human/hg38/mane.html @@ -1,27 +1,29 @@ <h2>Description</h2> <p> The <a href="https://www.ncbi.nlm.nih.gov/refseq/MANE/" target="_blank">Matched Annotation from NCBI and EMBL-EBI (MANE)</a> project aims to produce a matched set of high-confidence transcripts that are identically annotated between RefSeq (NCBI) and Ensembl/GENCODE (led by EMBL-EBI). Transcripts for MANE are chosen by a combination of automated and manual methods based on conservation, expression levels, clinical significance, and other factors. Transcripts are matched between the NCBI RefSeq and Ensembl/GENCODE annotations based on the GRCh38 genome assembly, with precise 5' and 3' ends defined by high-throughput sequencing or other available data.</p> -<p>This track is automatically updated, see the <b>source data version</b> above for the current version -number. MANE include almost all human protein-coding genes and genes of clinical relevance, including genes in the +<p> +This track is automatically updated, see the <b>source data version</b> above for the current +version number. MANE includes almost all human protein-coding genes and genes of clinical relevance, +including genes in the <a href="https://www.acmg.net/PDFLibrary/41436_2021_1172_OnlinePDF-1.pdf" target="_blank">American College of Medical Genetics and Genomics (ACMG) Secondary Findings list (SF) v3.0</a>. It includes both <b>MANE Select</b> and <b>MANE Plus Clinical</b> transcripts. <b>MANE Plus Clinical</b> items are <b><font color=red>colored red</font></b>. <p> For more information on the different gene tracks, including MANE vs GENCODE or RefSeq, see our <a href="/FAQ/FAQgenes.html#ens" target="_blank">Genes FAQ</a>.</p> <h2>Data Access</h2> <p> The raw data can be explored interactively with the <a href="../cgi-bin/hgTables" target="_blank">Table Browser</a>, or the <a href="../cgi-bin/hgIntegrator" target="_blank">Data Integrator</a>. For computational analysis, genome annotations are stored in a bigGenePred file that can be downloaded from the <a href="http://hgdownload.soe.ucsc.edu/gbdb/$db/mane/" target="_blank">download