83fd535ffd08aac398121175c71d9b9554c0eee1 max Thu Dec 4 10:51:30 2025 -0800 adding a few example motifs to short match track, no redmine diff --git src/hg/htdocs/goldenPath/help/oligoMatch.html src/hg/htdocs/goldenPath/help/oligoMatch.html index a65d71f6802..be585b2a5c6 100644 --- src/hg/htdocs/goldenPath/help/oligoMatch.html +++ src/hg/htdocs/goldenPath/help/oligoMatch.html @@ -4,21 +4,144 @@ the assembly sequence. It is useful for finding oligonucleotides, restriction sites, or other recurring short sequences within the assembly. In full display mode, each motif occurrence is labeled by the strand on which the match is located, followed by the starting coordinate of the match. In cases where the input motif sequence is identical to its reverse complement, only the match on the "+" strand is shown.

The track may be configured to search for any short sequence of 2 - 30 bases in length. Sequences may include IUPAC ambiguity codes. To change the motif, open the track's description page (by clicking the track control label or the mini-button to the left of the track), then type a new sequence into the text box.

To see how to create a bed file of the short match data see this mailing list question here.

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Example motifs

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CategoryMotif (Consensus)Name / FunctionNotes
Transcription initiationTATAWAARTATA boxClassic Pol II promoter element (~30 bp upstream of TSS).
Transcription initiationCCATNTTYY1 binding motifCommon promoter-associated TF motif.
Transcription initiationYYANWYYInitiator (Inr)Anchors transcription start when no TATA box is present.
Transcription terminationAATAAAPolyadenylation signal (PAS)Main poly(A) signal; variants include ATTAAA, TATAAA.
RNA modificationDRACHm⁶A methylation motifCore motif for METTL3/METTL14 deposition.
Splice donorMAGGTRAGT5′ splice site (donor)exon–intron boundary is after MAG.
Splice acceptorYYYYYYYYYNCAGG3′ splice site (acceptor), splice site is before last GLong pyrimidine tract + invariant AG.
Branch pointYNYURAYSplicing branch pointLocated upstream of the 3′ splice site; weak but conserved.
Transcription factorGATAGATA family motifRecognized by GATA1/2/3/4.
Transcription factorCACGTGE-boxRecognized by MYC/MAX and USF families.
Transcription factorTGASTCAAP-1 motif (Jun/Fos)Key stress-response motif; S = G/C.
Transcription factorCCGCCCSP1 motifClassic GC-rich promoter element.
Transcription factorGCGTGHIF1A/HRE variantHypoxia response element; canonical form is RCGTG.
Transcription factorGATTAHomeobox (HOX) coreGeneric homeodomain preference; flanking bases refine specificity.
RNA editingWAR (local context)ADAR A-to-I editing preferenceLess strict motif; enriched in dsRNA structures.
Replication originWAWTTDDWWORC-associated origin motifWeak consensus; human origins have low sequence specificity.
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Credits

This track was generated by Jim Kent of the UCSC Genome Bioinformatics Group.